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Draghia-Akli R. 2003 Maternal GHRH plasmid administration
changes pituitary cell lineage and improves progeny growth
of pigs. American Journal of Physiology: Endocrinology and
Metabolism. 285:E224-E231.
85) Khan AS, Anscombe IW, Cummings KK, Pope MA, Smith LC,
Draghia-Akli R. 2003 Effects of plasmid-mediated growth
hormone-releasing hormone supplementation on LL-2 adenocarcinoma
in mice. Molecular Therapy. 8:459-466.
86) Khan AS, Smith LC, Abruzzese RV, Cummings KK, Pope MA,
Brown PA, Draghia-Akli R. 2003 Optimization of Electroporation
Parameters for the Intramuscular Delivery of Plasmids in
Pigs. DNA and Cell Biology. 22(12):807-814.
87) Rabinovsky ED, Draghia-Akli R. 2004 Insulin-like Growth
Factor I Plasmid Therapy Promotes In Vivo Angiogenesis.
Molecular Therapy. 9(1):46-55.
88) Draghia-Akli R, Smith LC. 2003 Electrokinetic Enhancement
of Plasmid Delivery In Vivo. In: Templeton NS, Lasic DD
(eds) Gene Therapy -- Therapeutic Mechanisms and Strategies.
Marcel Dekker, Inc., New York, 245-263.
89) Khan AS, Smith LS, Anscombe IW, Cummings KK, Pope MA,
Draghia-Akli R. 2005 Growth hormone releasing hormone plasmid
supplementation, a potential treatment for cancer cachexia,
does not increase tumor growth in nude mice. Cancer Gene
Therapy. 12:54-60.
90) Tone CM, Cardoza DM, Carpenter RH, Draghia-Akli R. 2004
Long-term effects of plasmid-mediated growth hormone releasing
hormone in dogs. Cancer Gene Therapy. 11:389-396.
91) Draghia-Akli R, Fiorotto ML. 2004 A new plasmid-mediated
approach to supplement somatotropin production in pigs.
Journal of Animal Science. 82(E. Suppl.):E264-E269.
92) Brown PA, Davis WC, Draghia-Akli R. 2004 Immune-enhancing
effects of growth hormone-releasing hormone delivered by
plasmid injection and electroporation. Molecular Therapy.
10(4):644-651.
93) Khan AS, Brown PA, Draghia-Akli R. 2005 Plasmid-based
growth hormone releasing hormone supplementation and its
applications [review]. Current Opinion in Molecular Therapeutics.
7(4): 306-16.
94) Hebel H, Attra H, Khan AS, Draghia-Akli R. 2006 Successful
parallel development and integration of a plasmid-based
biologic, container/closure system and electrokinetic delivery
device. Vaccine. 24(21):4607-14.
95) Khan AS, Pope MA, Draghia-Akli R. 2005 Highly efficient
constant-current electroporation increases in vivo plasmid
expression. DNA and Cell Biology. 24(12), 810-8.
96) Draghia-Akli R, Khan AS, Pope MA, Brown PA. 2005 Innovative
electroporation for therapeutic and vaccination applications
[review]. Gene Therapy and Molecular Biology. 9: 329-338.
97) Draghia-Akli R, Pope MA, Brown PA, Khan AS. 2006 Plasmid-based
expression technology using growth hormone releasing hormone:
a novel method for physiologically stimulating long term
growth hormone secretion [review]. Combinatorial Chemistry
and High Throughput Screening. 9(3): 181-185.
98) Thacker EL, Holtkamp DJ, Khan AS, Brown PA, Draghia-Akli,
R. 2006 Plasmid-mediated GHRH efficacy in reducing disease
associated with Mycoplasma hyopneumoniae and porcine reproductive
and respiratory syndrome virus infection. Journal of Animal
Science. 84(3): 733-742.
99) Prud’homme GJ, Glinka Y, Khan AS, Draghia-Akli
R. 2006 Electroporation for the prevention or treatment
of immunological, endocrine and neoplastic diseases [review].
Current Gene Therapy. 6(2): 243-273.
100) Fiorotto ML, Lopez R, Oliver WT, Khan AS, Draghia-Akli
R. 2006 Transplacental transfer of a growth hormone releasing
hormone peptide from mother to fetus in the rat. DNA and
Cell Biology, 25(8): 429–437.
101) Brown PA, Khan AS, Draghia-Akli R. 2006 Delivery of
DNA into skeletal muscle in large animals. In “Electroporation
Protocols: Experimental and Clinical Medicine” ed.
Shulin Li. Humana Press. In press.
102) Draghia-Akli R and Khan AS. 2006 Muscle and fat mass
modulation in different clinical models. In “Electroporation
Protocols: Experimental and Clinical Medicine” ed.
Shulin Li. Humana Press. In press.
103) Prud’homme GJ, Draghia-Akli R, Wang Q. 2007 Plasmid-based
gene therapy of diabetes mellitus [review]. Gene Therapy.
14(7): 553-564.
104) Draghia-Akli R and Khan AS. 2007 In Vivo Electroporation
of Gene Sequences for Therapeutic and Vaccination Applications.
Recent Patents on DNA & Gene Sequences, 1:207-213.
105) Curcio C, Khan AS, Amici A, Spadaro M, Quaglino E,
Cavallo F, Forni G, Draghia-Akli R. 2008 DNA immunization
using constant-current electroporation affords long-term
protection from autochthonous mammary carcinomas in cancer-prone
transgenic mice. Cancer Gene Ther. Feb;15(2):108-14. Epub
2007 Nov 9
106) Hirao LA, Wu L, Khan AS, Satishchandran A, Draghia-Akli
R, Weiner DB. 2008 Intradermal/subcutaneous immunization
by electroporation improves plasmid vaccine delivery and
potency in pigs and rhesus macaques. Vaccine. Jan 17;26(3):440-8.
107) Cristillo AD, Weiss D, Hudacik L, Restrepo S, Galmin
L, Suschak J, Draghia-Akli R, Markham P, Pal R. 2008 Persistent
antibody and T cell responses induced by HIV-1 DNA vaccine
delivered by electroporation. Biochem Biophys Res Commun.
Feb 1;366(1):29-35.
108) Brown PA, Bodles-Brakhop AM, Draghia-Akli R. 2008 Plasmid
Growth Hormone Releasing Hormone Therapy in Healthy and
Laminitis-Afflicted Horses - Evaluation and Pilot Study.
J Gene Medicine, in press.
109) Bodles-Brakhop AM, Brown PA, Draghia-Akli R. 2008 Double-blinded,
placebo-controlled plasmid GHRH trial for cancer-associated
anemia in dogs. Molecular Therapy, in press.
110) Brown PA, Bodles-Brakhop AM, Draghia-Akli R. 2008 Reduction
of Morbidity and Mortality in Dairy Livestock and Enhancement
of Production Parameters by Plasmid-mediated Growth Hormone
Releasing Hormone Treatment during a Period of Heat Stress.
J Dairy Science, in revision.
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