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Research
at VGX™ Pharmaceuticals has demonstrated that this technology
increases plasmid uptake and, thus, expression by 1000-fold
over plasmid injection alone, to levels comparable to those
obtained using viral vectors |
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CELLECTRA®
device delivers a constant-current electrical field that maintains
a square-wave function through tissue – important for
successful EP |
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The
microprocessor-driven device is capable of measuring tissue
resistance and adapting output to varying individual conditions,
such as fat content in the muscle, skin thickness or changing
tissue resistance during the EP process |
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CELLECTRA®
device has built-in safety features, including an enabling
step – an electric field will not be generated if the
individual needles of EP needle- array are not inserted into
the target tissue, and furthermore, into the same muscle |
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Virtual elimination
of heat-related tissue damage, and consequently pain usually
involved with traditional EP methods |
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System
settings can be tailored to match your EP needs: depth of
tissue penetration, electric field intensity, lag time between
injection and EP, pulse duration, injection volume |
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CELLECTRA®
device can instantly detect errors before the electroporation
sequence is started, thus preventing waste of test substance |
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Machine
maintains settings to avoid mistakes between treated animals
– each animal number can be entered and stored in CELLECTRA® |
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EP data for each
pulse in each treated subject is recorded, and with the help
of built-in software, can be easily downloaded and analyzed |
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